This book provides a broad and in-depth guide to electron microscopy in renal disease. Practical and clinically focussed chapters cover all diseases encountered by renal pathologists within daily practice. High quality electron microscopy images illustrate the technical aspects of electron microscopy, approaches to ultrastructure, normal kidney structures, glomerular pathology, tubulo-interstitial pathologies, vascular pathology, and kidney transplantation.
Atlas of Renal Ultrastructural Pathology aims to give readers an understanding of the main ultrastructural patterns and is relevant to renal pathologists, nephrologists, and transplant pathologists, as well as Biomedical Scientists involved in Electron Microscopy.
1. Introduction.- 2. Technical aspects of EM in kidney and artefacts.- 3. Approach to US examination of Kidney.- 4. Normal kidney structures on EM.- 5. Acquired Glomerular diseases with deposits.- 6. Immune complex, predominantly non-organised glomerular diseases.- 7. Immune complex, predominantly organised glomerular diseases.- 8. Complement, organised and non-organised glomerular diseases.- 9. Light chains only (and amyloid in general).- 10. Acquired Glomerular diseases without deposits.- 11. Vasculitis/anti-GBM.- 12. Podocytopathies.- 13. Matrix.- 14. TMA.- 15. Innate glomerular diseases including storage diseases.- 16. Podocytopathies.- 17. Basement membrane structural abnormalities.- 18. Fabry’s and other storage.- 19. Coll III, Fibronectin.- 20. LCAT-deficiency and other lipoprotein things and other rare pediatric things.- 21. Hypertension.- 22. Tubulo-interstial pathologies.- 23. Acute tubular injury (toxic and ischemic).- 24. Mitochondrial.- 25. Viral infections not related totransplantation.- 26. Genetic including cystic diseases.- 27. Immune complex.- 28. Complement.- 29. Light chain.- 30. Xanthogranulomatous Pyelonephritis: Malakoplakia, rare non-viral infections?.- 31. Anticoagulant- Related Nephropathy.- 32. Heavy Metal Nephropathy (Lead and Cadmium Nephropathy).- 33. Vascular Pathologies.- 34. Arteriolar hyaline.- 35. Immune complexes.- 36. TMA.- 37. Atheroemboli.- 38. Transplantation introduction.- 39. Donor-derived changes.- 40. Recurrent Glom disease.- 41. Diabetic change.- 42. AMR.- 43. Viral infections seen in transplantation.- 44. Cyclosporin/Tacrolimus Nephrotoxicity.
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