Antibiotic Resistance and Nanotherapy is a comprehensive guide that takes an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. The book also tackles the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, Antibiotic Resistance and Nanotherapy is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance
1. Introduction To Planktonic and Biofilm-Mediated Antimicrobial Resistance and Role of Nanotechnology in Overcoming Biofilm-Mediated Antibiotic Resistance
2. Key Determinants of Antimicrobial Resistance: Exploring the Influence of Antibiotic Pollution on the Emergence of Multidrug-Resistant Microbes
3. Drug Resistance Mechanism in Intracellular Pathogens and Modulation
4. Drug Resistance Mechanism in Extracellular Pathogens and Modulation
5. Metal-based Nanomedicine Against Intracellular Pathogens
6. Polymer-based nanomedicine against intracellular pathogens
7. Lipid-based Nanomedicine Against Intracellular Pathogens
8. Metal-based Nanomedicine Against Extracellular Pathogens
9. Polymer-based Nanomedicine Against Extracellular Pathogens
10. Lipid-based Nanomedicine Against Extracellular Pathogens
11. Interaction Between Infected Host Cells and Nanodelivery Systems
12. Nanoformulations for Local and Targeted Delivery of Antimicrobial Agent and Their Impact on Gut Microbiota
13. Innovative Strategies Utilizing Nanoparticles to Disrupt C-Di-GMP and Quorum Sensing
14. CRISPR-Cas Systems for Antibiotic Resistance
15. Synergistic Effects of Natural Compounds and Repurposed Drugs in Nanotherapy: A Strategy to Combat Biofilm-Associated Infections
16. Safety, Ethical, Regulatory Issues, and Challenges of Nanotherapy for Antimicrobial Resistance
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