This groundbreaking book introduces the Quality Life Cycle Assessment (QLCA) model, a novel approach integrating product quality assessment and life cycle assessment in sustainable manufacturing. By incorporating environmental criteria alongside quality considerations during the virtual prototyping phase, the QLCA model revolutionizes decision-making for sustainable product development. This book bridges the gap between product improvement and LCA application, addressing the critical need for sustainability in modern manufacturing. Leveraging digital technologies such as Big Data, Data Analytics, and Digital Twin, this book demonstrates how to construct virtual product models with comprehensive LCA integration. The QLCA model, particularly suited for smart factories, supports innovation and informed decision-making in sustainable product development. Aimed at students, research and development managers, and engineers, this volume offers practical guidance on balancing customer satisfaction with environmental impact throughout a product's lifecycle. By elucidating the application of LCA in product lifecycle assessment and its combination with quality considerations during prototyping, this book provides invaluable insights for practitioners navigating the complexities of sustainable manufacturing in the digital age.