This comprehensive volume explores the dynamic intersection of medicine and technology, emphasizing innovative advancements and their impact on healthcare. It covers a broad range of topics, including Concept of digital twins, Assistive and point-of-care health devices, Creation and application of engineered materials that are designed to improve medical treatments and patient outcomes, Development of indigenous left ventricular assist devices (LVAD) and percutaneous ventricular assist devices (PVAD) , Optical tools for healthcare are examined including advancements in imaging, diagnostics, and minimally invasive surgical techniques, Cancer technologies that are  showcasing cutting-edge innovations in detection, treatment, and research that is transforming oncology. The book also covers platform technologies aimed at combating infectious diseases, such as rapid diagnostic tools, antimicrobial surfaces, and novel therapeutic strategies. Integration of robotics in healthcare is discussed, detailing advancements in surgical robots, rehabilitation devices, and robotic-assisted care. Together, these topics provide a detailed overview of how emerging technologies are revolutionizing traditional medicine and shaping the future of healthcare. This book will be valuable for the students and professionals working on the cutting-edge point-of-care biomedical devices, medical robotics, disease biology, and technology in medicine. It will be a useful resource for scientists and engineers interested in biomedical research problems.