In this issue of Sleep Medicine Clinics, guest editors Drs. Ray Chaudhury, Karolina Poplowska-Domaszewics, and Naomi Limbachiya bring their considerable expertise to the topic of Synucleinopathies and Sleep. Patients with synucleinopathies often experience disrupted sleep patterns, such as insomnia, excessive daytime sleepiness, REM sleep behavior disorder, and sleep fragmentation. These sleep disturbances can have a significant impact on overall quality of life, and understanding and managing them are crucial aspects of appropriate and effective care and treatment plans. Contains 17 relevant, practice-oriented topics including diversity, ethnic differences, sleep dysfunction, and Parkinson's disease; dementia with Lewy bodies and sleep dysfunction; Parkinson's disease and restless legs syndrome; clinical and molecular biomarkers of sleep dysfunction in Parkinson's disease; deep brain stimulation and Parkinson's disease; early onset Parkinson's disease and sleep dysfunction; and more Provides in-depth clinical reviews on synucleinopathies and sleep, offering actionable insights for clinical practice Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews