Recent Advances in Targeting Inflammation: Ion Channels, GPCR Signaling Tools, Therapies, and Beyond delves into the multifaceted occurrences of inflammation across different systems, such as neuroinflammation and gastric inflammation. The book's main goal is to present the latest highlights, covering advancements in inflammation, investigational therapies, animal models, and biomarkers. These insights are crucial for better diagnosis, monitoring, and potential therapeutic options for patients suffering from both acute and chronic inflammation. This comprehensive work explores various topics, including ion channel regulation in inflammation, GPCR regulation, signaling pathways, and therapeutic approaches.
It emphasizes the importance of understanding the role of ion channels, GPCR, and nutrition in managing inflammation effectively. Additionally, the book discusses the global impact of chronic inflammation on health outcomes, stressing the need for improved healthcare planning and strategies.
Section 1: Introduction
1. Introduction: Voltage gated ion channels and GPCR signaling in inflammation
2. Calcium – dependent regulation of ion channels in inflammation
3. Role of GPCR signaling in Neuroinflammation
Section 2: Ion channels regulation in inflammation
4. Unveiling the Significance of Mitochondrial Ion Channels in Inflammatory Responses
5. Neuroinflammation with regards to ion Channels dysregulation
Section 3: GPCR regulation in inflammation
6. Role of GPCRs in Inflammasome activation and Therapeutics
7. GPCR modulated inflammatory responses in liver : A transitional move from NAFLD to NASH
8. Molecularity of GPCR Signaling involved in Neuroinflammation
9. GPCR regulation of chemokine, lipid mediator and neuropeptide receptors in inflammation
Section 4: Signaling Pathways in Inflammation
10. G protein-coupled receptors: structure- and function-based drug discovery
11. Alteration of inflammatory Signaling network in cancer
12. Role of MAPK in Neuroinflammation: A molecular approach
Section 5: Therapeutic approaches for inflammation
13. G-protein-coupled receptors (GPCRs) in the treatment of diabetes
14. Application of Nanoparticles for Targeting G Protein-Coupled Receptors
15. Therapeutic approaches for inflammation
16. Nano-therapeutic strategies for inflammation via GPCR modulation: An update
17. Innovative GPCR Targeting Strategies in Drug Therapy for Inflammatory Diseases: Mechanistic Approaches
18. Distinctive application of nano-therapeutics in mitigating inflammation
19. Therapies targeting ion channels and GPCRs
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