Genome Editing and Nanotechnology-Based Treatment for Breast Cancers delves deeply into the multifaceted nature of breast cancer. It begins with a thorough introduction to the disease, detailing its histological and molecular subtypes and then moves on to explain methods for early detection and imaging techniques. The book also explores various treatment options, focusing on innovative technologies like genome editing and nanotechnology. In its nine sections, the book probes the elements that contribute to breast cancer metastasis and discusses the potential of genome editing tools for creating tailor-made drugs.
Users will find this to be a crucial resource for researchers, graduate students in cancer research and bioinformatics, oncologists, and anyone seeking to expand their understanding of the field.
1. Introduction to Breast cancer
2. Histological and Molecular subtypes of breast cancer based on PAM50 RNA-based gene signature
3. Biomarkers-Prognostic parameters for different molecular subtypes of breast cancer
4. Tumor suppressor genes-leading cause of breast cancer
5. Single nucleotide polymorphism in breast cancer susceptibility genes
6. Metabolomic profiling of breast cancer patient
7. Non-invasive methods for early detection of breast cancer
8. Breast cancer imaging techniques
9. Possible treatments of breast cancer
10. Genome based targeted therapies for treatment of breast cancer
11. CRISPR technology for diagnosis of breast cancer
12. Pharmacokinetics and pharmacodynamics of nano-particles based delivery systems.
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