In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesity. Top experts in the field cover the latest research regarding weight loss drugs, drug safety, pharmacotherapy, AI, and nutritional/lifestyle changes for managing obesity. Contains 15 relevant, practice-oriented topics including drug safety and pharmacovigilance of anti-obesity medications; obesity stigma; non-pharmacological treatment for obesity; artificial intelligence and obesity management; intermittent fasting and obesity; and more. Provides in-depth clinical reviews on obesity, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.