This volume contains the papers presented at the 12th International Conference on Production Research – Americas, ICPR Americas 2024. The focus and theme of the conference was Intelligent Production and Industry 5.0 with Human touch, Resilience, and Circular Economy. The conference had the majority of authors from the Western Hemisphere, thus providing readers with the current research topics and results in that region towards establishing Industry 5.0 and resilient, intelligent production methods in the theory and practice of production research. As such, the volume establishes direction for the further advancement of circular economy and human advancement. What areas are covered? The book covers the broad area of production research, including the following topics: Intelligent Production for Circular Economy, Smart Factories and Industrial Internet of Things, Sustainable Manufacturing and Engineering, Modelling and Simulation of Manufacturing and Services, Strategies and Approaches to Develop Production Resilience, Digital and Cyber Manufacturing and Services for Industry 4.0 & 5.0, Data Analytics and Smart Manufacturing, Manufacturing Systems and Supply Chains, Human Factors Engineering, and many others shown inside the book. What is the main focus? The presented papers cover new theories in production research, with emphasis on digital and smart manufacturing, lean and agile manufacturing, and sustainable manufacturing and engineering. However, as the ICPR conferences also cover applications of developed theories in industry, it is expected that about 1/3 of papers will have application focus. Who will be interested in reading? The book aims to get the attention of graduate students and early researchers eager to learn new methodologies and theories of production research as its primary audience. However, advanced undergraduate students may also be tempted to learn the topics of the conference as a potential medium in their choices of careers, particularly when considering graduate degrees. This is the first edition of the book, but it also continues the tradition of proceedings from previous ICPR global and regional conferences.