Immunological Insights and Emerging Therapeutics in Medical Mycology summarizes the current knowledge on interactions between host cells and human fungal pathogens and explains how certain immune defects lead to vulnerability to fungal infection.
Chapters focus on immune response to such fungal infections as candidiasis, aspergillus, cryptococcosis, mucormycosis, pneumocystis.This title provides a basis for further study on antifungal immunity by enhancing understanding of antifungal immune responses. Further, this title offers new insights from the host immune response, improving understanding of disease pathogenesis and informing novel prophylactic and therapeutic approaches to fungal infections.
1. Antifungal Host Defenses and the Risk of Invasive Fungal Infection
2. The IL-17 Pathway and Mucosal Candidiasis
3. The Importance of Spleen Tyrosine Kinase (Syk) in the Immune Response to Candidiasis
4. Dectin-1, Interferon Expression and the Host Immune Response Against Aspergillus fumigatus
5. The Role of Pentraxin-3 in Invasive Aspergillosis
6. Breaches in Antifungal Immunity and Viral-Associated Aspergillosis
7. CARD-9-Dependent Neutrophil Recruitment and Fungal Infection
8. Dendritic Cell Responses to Cryptococcal Infection
9. Development of Glucan Particle-Based Vaccines for Cryptococcosis
10. Tissue Invasion in Mucormycosis and the Role of Coat Protein Homologs
11. TNF-alpha Antagonists and Susceptibility to Histoplasmosis
12. Genetic Predisposition to Disseminated Coccidioidomycosis
13. Anti-CD20 Therapy and Risk of Pneumocystis Pneumonia
14. Bruton Tyrosine Kinase Inhibitors and Risk of Fungal Infection
15. Bioengineering T-cells to Treat Invasive Aspergillus Infection
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