This established handbook is unique in illustrating and reviewing the cell and extracellular matrix, organelle by organelle (with numerous subsections) with emphasis on human pathology. Anyone studying normal or pathological tissues whether human, animal, or tissue culture, by conventional transmission electron microscopy for diagnosis or research, will use this book to understand what it is they are examining—without having to go through large volumes of previously published articles.
Key Features:
Illustrates cell ultrastructure with electron micrographs
Reviews extracellular matrix structure
Assists pathologists in diagnosis of cellular pathologies
Includes contributions from an international team of leading researchers
Chapter 1. The Nucleus. Chapter 2. Centrosomes. Chapter 3. Mitochondria. Chapter 4. The Golgi Apparatus and Secretory Granules. Chapter 5. Endoplasmic reticulum. Chapter 6. Annulate lamellae - nucleopore complexes and tubulohelical membrane arrays. Chapter 7. Lysosomes. Chapter 8. Microbodies (peroxisomes and microperoxisomes). Chapter 9. Melanosomes. Chapter 10. Rod-shaped microtubulated bodies (Weibel-Palade bodies). Chapter 11. Intracytoplasmic Filaments. Chapter 12. Microtubules. Chapter 13. The cytosol (cytoplasmic matrix) and its inclusions. Chapter 14. Cell membrane and coat. Chapter 15. Cell junctions. Chapter 16. Cilia and flagella. Chapter 17. Extracellular matrix (extracellular components). Chapter 18. Exocytosis, endocytosis, cell-in-cell phenomena, cell surface structures, and glomerular podocytes (microvilli and foot processes). Chapter 19. The early development of electron microscope technology and techniques in biology and the biomedical sciences. Chapter 20. Current advances in Electron Microscopy technology and techniques with postulated applications in pathology.
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