Tic Disorders and Tourette Syndrome provides a comprehensive overview of the clinical aspects, treatments, and research on tic disorders and Tourette syndrome. Clinical aspects span primary to secondary and functional tics and their differential diagnosis. Subsequent chapters discuss common neuropsychiatric comorbidities including obsessive-compulsive disorder, ADHD, mood disorders, intermittent explosive disorder, and others. Subsequent sections cover epidemiology, etiology, and pathophysiology of tics, treatment of tics, and clinical scales to evaluate tics and how to utilize these scales in the context of specific treatments.Video accompaniment shows clinical presentations, and animal models.The volume provides introductory accessible knowledge for neurologists, psychiatrists, neuropsychiatrists and psychologists, but also expert up-to-date knowledge for the advanced reader
1. Introduction
2. Georges Gilles de la Tourette in the history of tics
Section 1. Clinical Diagnosis of Tics
3. Clinical presentation of tics and Gilles de la Tourette syndrome
4. Secondary Tics: Etiology, presentation and management
5. Functional tics and tic-like behaviors
6. Repetitive and restricted behaviors, habits, body-focused repetitive behaviors and motor stereotypies
Section 2. Comorbidities in Primary Tic Disorders
7. OCD in primary tic disorders and Tourette syndrome
8. Attention-deficit/hyperactivity disorder in primary tic disorders and Tourette Syndrome
9. Explosive outbursts and Tourette Syndrome/Chronic tic disorder
10. Sleep in tic disorders and Tourette Syndrome
11. Autism spectrum and other neurodevelopmental disorders
12. Sexuality and sexual health in primary tic disorders
Section 3. Etiology and Pathophysiology
13. Epidemiology of Tourette Syndrome
14. Genetics of tic disorders and Tourette Syndrome
15. Neuroimmunology of tics and Gilles de la Tourette syndrome
16. Animal models of Gilles de la Tourette syndrome and other tic disorders
17. Clinical neurophysiology of tics
18. Neuroimaging of tic disorders
19. Dopamine and other neurotransmitters
20. Premonitory urges and other sensory phenomena in primary tic disorders
21. Inhibitory control and voluntary tic suppression
Section 4. Treatments
22. Behavioral treatments of tic disorders
23. Pharmacological treatments
24. Deep brain stimulation for Gilles de la Tourette syndrome
25. Non-invasive brain stimulation for Gilles de la Tourette syndrome
26. Treatment of neuropsychiatric comorbidities in tic disorders
Section 5. Overview of patient organizations and other useful resources
27. Overview of support associations and other useful resources
Section 6. Closing Remarks and Future
28. Closing remarks and future scope of unmet needs
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