Serving as an essential pedagogical tool, this Research Handbook captures the multifaceted nature of contemporary tourism from a variety of academic perspectives, including health, sociology and heritage. Through this interdisciplinary approach, it consolidates current tourism research while addressing the vast potential for further study. The Research Handbook on Tourism, Complexity and Uncertainty encourages a holistic understanding of the dynamic nature of the tourism industry. It investigates a plethora of challenging subjects such as conflicts between tourists and locals, the exploitation of locals, and inequalities exacerbated by the COVID-19 pandemic, examining how and why these problems occur. Analysis by esteemed contributors showcases the fragile nature of the industry when affected by political and sociological changes, while providing solutions to potential threats that may compromise it. This illuminating Research Handbook is vital for researchers and academics focusing on tourism, hospitality and the experience economy. It is also of great benefit to students within these areas seeking to explore the future of tourism research.