This book aims to provide the university-level student and educator with a convenient means for testing depth of knowledge and developing problem-solving ability by enabling wide-ranging problems to be tackled without the support of a textbook framework. A solid foundation in physical chemistry concepts is fundamentally important for those wishing to make meaningful contributions to a diverse array of rapidly developing fields including renewable energy, environmental sustainability, biomedical technology, and material science and engineering. Effective solutions to real-world technological challenges require depth of knowledge and an ability to solve problems outside the usual contextual structure found in standard physical chemistry textbooks. By using this book together with Physical Chemistry Problems and Solutions: Atoms, Molecules and Thermodynamics, in which nearly nine hundred problems are provided, the reader is able to identify knowledge gaps quickly and readily address them by consulting the accompanying comprehensively worked solutions. This approach of presenting probing questions "in isolation" fosters a deeper understanding of the subject and the development of problem-solving skills.