In this issue of Foot and Ankle Clinics, guest editor Dr. Camilla Maccario brings her considerable expertise to the topic of Osteochondral Lesions of the Foot and Ankle. Top experts in the field cover key topics in this challenging area to help surgeons stay up-to-date on basic science, imaging, and treatment principles for osteochondral lesions. Contains 16 relevant, practice-oriented topics including ankle cartilage: chondral and osteochondral lesions-terminology, etiology, reasons for pain; OLT: quality of life, lesion size and lesion site; pre- and post-operative imaging and outcomes scores for cartilage repair of the ankle; weight-bearing MRI and CT scan: correlations to improve osteochondral lesion understanding; cartilage injuries: basic science update; and more. Provides in-depth clinical reviews on osteochondral lesions of the foot and ankle, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.