Phytochemicals in Cancer Therapy and Beyond examines the role of natural products in the treatment of diseases, especially cancer. With a strong focus on the treatment of diseases, it demonstrates the mechanisms that natural products follow in treatment. In 24 chapters, the book describes not only regular cancer treatments, challenges, and developments in cancer treatment, in particular, phytochemicals and cellular mechanisms in cancer therapy, phytochemicals and molecular pathways in cancer, and Nano-scale delivery systems for phytochemicals in cancer therapy. The book concludes with clinical applications of phytochemical therapies. This book is a valuable resource for researchers in the field of oncology, disease therapy, diabetes mellitus treatment, cellular signaling scientists, and nanomaterial engineers.
Section I: Cancer treatment and challenges
1: New developments in treatment of cancer
2: A summary of molecular pathways responsible for cancer progression
3: Challenges in treatment of cancer with conventional strategies
Section II: Phytochemicals and cancer therapy
4: Phytochemicals in suppressing cancer proliferation
5: Phytochemicals in suppressing cancer metastasis
6: Phytochemicals in providing cancer therapy sensitivity
Section III: Phytochemicals in the treatment of other diseases
7: Phytochemicals in treatment of Diabetes mellitus
8: Phytochemicals in treatment of neurological diseases
9: Phytochemicals in treatment of ischemic/reperfusion injury
10: Phytochemicals in treatment of infectious diseases
Section IV: Phytochemicals and cellular mechanisms in cancer therapy
11: Phytochemicals in regulating glycolysis in cancer
12: Phytochemicals in regulating apoptosis in cancer
13: Phytochemicals in regulating autophagy in cancer
14: Phytochemicals in regulating EMT and MMPs in cancer
Section V: Phytochemicals and molecular pathways in cancer
15: Phytochemicals in regulating STAT3 signaling in cancer
16: Phytochemicals in regulating Wnt signaling in cancer
17: Phytochemicals in regulating NF-kB signaling signaling in cancer
18: Phytochemicals in regulating PTEN/PI3K/Akt signaling in cancer
19: Phytochemicals in regulating non-coding RNAs in cancer
Section VI: Nano-scale delivery systems for phytochemicals in cancer therapy
20: Polymeric nanoparticles for delivery of phytochemicals in cancer therapy
21: Lipid-based nanoparticles for delivery of phytochemicals in cancer therapy
22: Carbon- and metal-based nanomaterials for delivery of phytochemicals in cancer therapy
Section VII: Clinical applications
23: Application of phytochemicals in clinical trials for treatment of diseases and malignant tumors
24: The market of natural products around the world
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