Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species.
This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
SECTION I ETHICAL, REGULATORY, and SCIENTIFIC CONSIDERATIONS 1. Ethical Considerations 2. Regulatory Considerations, US and International 3. Optimising anaesthesia and analgesia for specific research projects
SECTION II PRINCIPLES of ANESTHESIA and ANALGESIA 4. Injectable Anesthetics including Delivery Systems (where applicable) 5. Anesthetic Adjuncts including Sedatives, Tranquilizers, and Local Anesthetics 6. Inhalant Anesthetics including Delivery and Safety 7. Analgesics including Novel Delivery Systems (eg oral, transdermal, slow release formulations etc) 8. Neuromuscular Blocking Agents
SECTION III ANESTHETIC EQUIPMENT and MONITORING 9. Anaesthetic equipment (ventilators etc) 10. Monitoring of Anesthesia
SECTION IV PERIPROCEDURAL CARE 11. General Care: During and after the Procedure 12. Assessing Pain in Laboratory Species 13. Pain management in Laboratory Species
SECTION V PRACTICAL CONSIDERATIONS BY SPECIES 14. Anesthesia and Analgesia in Rodents 15. Anesthesia and Analgesia in Rabbits 16. Anesthesia, Restraint and Analgesia of Laboratory Fishes 17. Anesthesia and Analgesia in Swine 18. Anesthesia and Analgesia in Nonhuman Primates 19. Anesthesia and Analgesia in Dogs and Cats 20. Anesthesia and Analgesia of Ruminants 21. Anesthesia and Analgesia in Ferrets 22. Anesthesia and Analgesia in Other Mammals 23. Anesthesia and Analgesia in Birds 24. Anesthesia and Analgesia in Reptiles 25. Anesthesia and Analgesia in Amphibians 26. Anesthesia and Analgesia of Invertebrates
SECTION VI SPECIAL TOPICS 27. Management of Chronic Pain 28. Anesthesia and Analgesia in the Fetus and Neonate 39. Anesthetic Considerations for In Vivo Imaging Studies 30. The Study of Pain
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