Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species.
This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research.
SECTION I ETHICAL, REGULATORY, and SCIENTIFIC CONSIDERATIONS
1. Ethical Considerations
2. Regulatory Considerations, US and International
3. Optimising anaesthesia and analgesia for specific research projects
SECTION II PRINCIPLES of ANESTHESIA and ANALGESIA
4. Injectable Anesthetics including Delivery Systems (where applicable)
5. Anesthetic Adjuncts including Sedatives, Tranquilizers, and Local Anesthetics
6. Inhalant Anesthetics including Delivery and Safety
7. Analgesics including Novel Delivery Systems (eg oral, transdermal, slow release formulations etc)
8. Neuromuscular Blocking Agents
SECTION III ANESTHETIC EQUIPMENT and MONITORING
9. Anaesthetic equipment (ventilators etc)
10. Monitoring of Anesthesia
SECTION IV PERIPROCEDURAL CARE
11. General Care: During and after the Procedure
12. Assessing Pain in Laboratory Species
13. Pain management in Laboratory Species
SECTION V PRACTICAL CONSIDERATIONS BY SPECIES
14. Anesthesia and Analgesia in Rodents
15. Anesthesia and Analgesia in Rabbits
16. Anesthesia, Restraint and Analgesia of Laboratory Fishes
17. Anesthesia and Analgesia in Swine
18. Anesthesia and Analgesia in Nonhuman Primates
19. Anesthesia and Analgesia in Dogs and Cats
20. Anesthesia and Analgesia of Ruminants
21. Anesthesia and Analgesia in Ferrets
22. Anesthesia and Analgesia in Other Mammals
23. Anesthesia and Analgesia in Birds
24. Anesthesia and Analgesia in Reptiles
25. Anesthesia and Analgesia in Amphibians
26. Anesthesia and Analgesia of Invertebrates
SECTION VI SPECIAL TOPICS
27. Management of Chronic Pain
28. Anesthesia and Analgesia in the Fetus and Neonate
39. Anesthetic Considerations for In Vivo Imaging Studies
30. The Study of Pain
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