Seldin and Giebisch's The Kidney (6 ed)
Physiology and Pathophysiology

Edited by Michael Caplan,Orson W. Moe,Robert J. Alpern,Michael J. Caplan,Susan E. Quaggin

ISBN13: 9780128153895

Imprint: Academic Press Inc

Publisher: Elsevier Science Publishing Co Inc

Format:

Published: 01/02/2025

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Description
Seldin and Giebisch’s The Kidney, Sixth Edition: Physiology and Pathophysiology provides a common language for nephrology researchers, fellows and practicing nephrologists to discuss normal and abnormal renal physiology and the development and diagnosis of a wide range of renal diseases. Guided by a team of four distinguished authorities in nephrology, experts from all areas of renal research and practice take readers from the structure and function of normal renal physiology, to the specific cellular and molecular mechanisms underlying disease development, and into the management of renal disease through physiologic regulation.This classic nephrology reference for nearly 30 years combines basic and clinical sciences that provides authoritative, concise and readily accessible information. Academic, medical and pharma researchers save valuable time by quickly accessing the very latest details on renal physiology and pathophysiology as opposed to searching through thousands of journal articles.
Volume 1 I: Epithelial and Nonepithelial Transport and Regulation 1. Epithelial Cell Structure and Polarity 2. Mechanisms of Ion Transport across Cell Membranes 3. Renal Ion-Translocating ATPases 4. Mechanisms of Water Transport Across Cell Membranes and Epithelia 5. Cell Volume Control 6. Solute Transport, Energy Consumption, and Production in the Kidney 7. Electrophysiological Analysis of Transepithelial Transport 8. Renal Ion Channels, Electrophysiology of Transport, and Channelopathies 9. Microvascular Permeability and the Exchange of Water and Solutes Across Microvascular Walls 10. External Balance of Electrolytes and Acids and Alkali 11. Renal Cilia Structure, Function, and Physiology 12. Intercellular Junctions 13. Principles of Cell Signaling 14. Scaffolding Proteins in Transport Regulation 15. The Renin–Angiotensin System 16. Neural Control of Renal Function 17. Eicosanoids and Renal Function 18. Extracellular Nucleotides and Renal Function 19. Paracrine Regulation of Renal Function by Dopamine II: Structural and Functional Organization of the Kidney 20. Structural Organization of the Mammalian Kidney 21. Biophysical Basis of Glomerular Filtration 22. Glomerular Cell Biology 23. Function of the Juxtaglomerular Apparatus: Control of Glomerular Hemodynamics and Renin Secretion 24. Renal Cortical and Medullary Microcirculations: Structure and Function 25. Molecular and Cellular Mechanisms of Kidney Development 26. Molecular and Cellular Mechanisms of Glomerular Capillary Development 27. Postnatal Renal Development 28. Renal Hyperplasia and Hypertrophy 29. Stem Cells and Generation of New Cells in the Adult Kidney III: Fluid and Electrolyte Regulation and Dysregulation 30. Epithelial Na+ Channels 31. Anion Channels 32. Physiology and Pathophysiology of the NaCl Co-Transporters in the Kidney 33. Sodium and Chloride Transport: Proximal Nephron 34. Sodium Chloride Transport in the Loop of Henle, Distal Convoluted Tubule, and Collecting Duct 35. Mineralocorticoid Action in the Aldosterone Sensitive Distal Nephron 36. Inherited Disorders of Renal Salt Homeostasis: Insights from Molecular Genetics Studies 37. Natriuretic Hormones 38. Pathophysiology of Sodium Retention and Wastage 39. Physiology and Pathophysiology of Hypertension 40. Physiology and Pathophysiology of Diuretic Action 41. Aquaporin Water Channels in Mammalian Kidney 42. Thirst and Vasopressin 43. The Urine Concentrating Mechanism and Urea Transporters 44. Hyponatremia 45. Hypernatremic States 46. Polyuria and Diabetes Insipidus 47. The Molecular Biology of Renal K+ Channels 48. Extrarenal Potassium Metabolism 49. Regulation of K+ Excretion 50. Physiopathology of Potassium Deficiency Volume II 51. Clinical Disorders of Hyperkalemia 52. Control of Intracellular pH 53. SLC4 Sodium-Driven Bicarbonate Transporters 54. The SLC4 Anion Exchanger Gene Family 55. Cellular Mechanisms of Renal Tubular Acidification 56. Chemoreceptors, Breathing and pH 57. Renal Ammonium Ion Production and Excretion 58. Clinical Syndromes of Metabolic Alkalosis 59. Clinical Syndromes of Metabolic Acidosis 60. Respiratory Acid–Base Disorders 61. Mechanisms and Disorders of Magnesium Metabolism 62. Calcium Channels 63. The Calcium-Sensing Receptor 64. Renal Calcium Metabolism 65. The Hormonal Regulation of Calcium Metabolism 66. Disorders of Calcium Metabolism 67. Pathogenesis and Treatment of Nephrolithiasis 68. Proximal Tubular Handling of Phosphate 69. Clinical Disturbances of Phosphate Homeostasis 70. Glucose Reabsorption in The Kidney 71. Kidney Transport of Amino Acids and Oligopeptides, and Aminoacidurias 72. Organic Anion and Cation Transporters in Renal Elimination of Drugs 73. Renal Filtration, Transport, and Metabolism of Albumin and Albuminuria IV: Pathophysiology of Renal Disease 74. Physiologic Principles in the Clinical Evaluation of Electrolyte, Water, and Acid–Base Disorders 75. Biomarkers for Assessment of Renal Function During Acute Kidney Injury 76. Pathophysiology of Acute Kidney Injury 77. Ischemic Renal Disease 78. Pathophysiology and Pathogenesis of Diabetic Nephropathy 79. Renal Failure in Cirrhosis 80. Autosomal Dominant Polycystic Kidney Disease 81. Renal Physiology and Disease in Pregnancy 82. Immune and Inflammatory Glomerular Diseases 83. Immunologic Mechanisms of Vasculitis 84. Genetic Abnormalities in Glomerular Function 85. Cellular Mechanisms of Drug Nephrotoxicity 86. Role of Glomerular Mechanical Stress in the Pathogenesis of Chronic Kidney Disease 87. Role of Proteinuria in the Progression of Renal Disease 88. The Inflammatory Response to Ischemic Acute Renal Injury 89. Catalytic (Labile) Iron in Kidney Disease 90. Chronic Kidney Disease: Pathophysiology and the Influence of Dietary Protein 91. Management of Calcium and Bone Disease in Renal Patients 92. Hematopoiesis and the Kidney 93. Individualizing the Dialysate to Address Electrolyte Disturbances in the Dialysis Patient 94. Homeostasis of Solute and Water by the Transplanted Kidney 95. Renal Disposition of Drugs and Translation to Dosing Strategies
  • Physiology
  • Urology & urogenital medicine
  • Professional & Vocational
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List Price: £425.00