While knowledge on substance abuse and addictions is expanding rapidly, clinical practice still lags behind. This state-of-the-art book brings together leading experts to describe what treatment and prevention would look like if it were based on the best science available. The volume incorporates developmental, neurobiological, genetic, behavioral, and social–environmental perspectives. Tightly edited chapters summarize current thinking on the nature and causes of alcohol and other drug problems; discuss what works at the individual, family, and societal levels; and offer robust principles for developing more effective treatments and services.
I. Introduction 1. Defining and Addressing the Problem, Kathleen M. Carroll and William R. Miller 2. The Forest and the Trees: Addiction as a Complex Self-Organizing System, Warren K. Bickel and Marc N. PotenzaII. Biological Factors 3. The Neurobiology of Addiction: A Hedonic Calvinist View, George F. Koob 4. What Can Human Brain Imaging Tell Us about Vulnerability to Addiction and to Relapse?, Anna Rose Childress 5. Genetics of Substance Use Disorders, Deborah Hasin, Mark Hatzenbuehler, and Rachel WaxmanIII. Psychological Factors 6. Natural Change and the Troublesome Use of Substances: A Life-Course Perspective, Carlo C. DiClemente 7. Developmental Perspectives on the Risk for Developing Substance Abuse Problems, Victor M. Hesselbrock and Michie N. Hesselbrock 8. Comorbid Substance Use Disorders and Psychiatric Disorders, Kim T. Mueser, Robert E. Drake, Win Turner, and Mark McGovern 9. Motivational Factors in Addictive Behaviors, William R. MillerIV. Social Factors 10. Racial and Gender Differences in Substance Abuse: What Should Communities Do about Them?, Harold D. Holder 11. Family and Other Close Relationships, Barbara S. McCrady 12. Social Contexts and Substance Use, Rudolf H. Moos 13. Ethnography and Applied Substance Misuse Research: Anthropological and Cross-Cultural Factors, Robert G. CarlsonV. Interventions 14. Behavioral Therapies: The Glass Would Be Half Full If Only We Had a Glass, Kathleen M. Carroll and Bruce J. Rounsaville 15. Pharmacotherapy of Addictive Disorders, Stephanie S. O'Malley and Thomas R. Kosten 16. Religion, Spirituality, and the Troublesome Use of Substances, Keith Humphreys and Elizabeth Gifford 17. What We Need Is a System: Creating a Responsive and Effective Substance Abuse Treatment System, A. Thomas McLellan 18. Drawing the Science Together: Ten Principles, Ten Recommendations, William R. Miller and Kathleen M. Carroll
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